5 Key Facts About 1,4-Butanediol (BDO)

31 Jul.,2025

1,4-Butanediol is an industrial solvent and intermediate used in the production of various plastics and polymers. When ingested, it is rapidly absorbed and metabolised to form γ-hydroxybutyrate (GHB), a neuromodulator that exerts potent depressant effects on the central nervous system.

 

1,4-Butanediol is an industrial solvent and intermediate used in the production of various plastics and polymers. When ingested, it is rapidly absorbed and metabolised to form γ-hydroxybutyrate (GHB), a neuromodulator that exerts potent depressant effects on the central nervous system.

 

1,4-Butanediol (BDO) is a versatile chemical compound with significant applications in various industries. Below are five essential facts about this valuable substance:

 

{CAS 110-63-4 1,4-Butanediol BDO}

 

1. Chemical Properties and Structure

 

1,4-Butanediol, commonly abbreviated as BDO, has the molecular formula C4H10O2. It is a diol, meaning it contains two hydroxyl (-OH) groups. This makes it highly reactive and suitable for use as an intermediate in chemical synthesis. At room temperature, BDO is a colorless, viscous liquid with a slightly sweet odor.

 

Key Properties:

- Molecular Weight: 90.12 g/mol  

- Boiling Point: Approximately 230°C  

- Solubility: Fully miscible in water and many organic solvents  

 

2. Industrial Applications

 

BDO is a cornerstone in the production of various chemicals, materials, and products. Its applications span multiple industries, including:

 

- Polymer Production: BDO is a key raw material in manufacturing polybutylene terephthalate (PBT), a thermoplastic polymer used in automotive and electrical components.  

- Spandex Fibers: Used to produce tetrahydrofuran (THF), a precursor for spandex fibers.  

- Solvents: Its derivatives, such as gamma-butyrolactone (GBL), are used as industrial solvents.  

- Pharmaceuticals and Cosmetics: Plays a role in synthesizing active pharmaceutical ingredients (APIs) and as a humectant in cosmetics.  

 

3. Green Production Methods

 

Traditionally, BDO has been produced through petrochemical processes, such as the Reppe process, which involves acetylene and formaldehyde. However, there is a growing shift towards bio-based production of BDO using renewable feedstocks like sugar, starch, and biomass. This aligns with global efforts to reduce carbon footprints and promote sustainable chemical production.

 

4. Safety and Handling

 

BDO requires careful handling due to its potential health and safety risks. It is non-volatile but can cause irritation upon skin or eye contact. Inhalation or ingestion of BDO in significant amounts may lead to toxic effects. Proper protective equipment, including gloves and goggles, is recommended when handling BDO in industrial or laboratory settings.

 

Precautions:

- Store in a cool, dry place away from direct sunlight and incompatible substances.

- Ensure adequate ventilation in areas where BDO is used.  

- Follow local regulations for safe disposal of chemical waste.  

 

5. Market Demand and Growth

 

The global market for BDO has been experiencing steady growth, driven by its demand in the polymer and solvent sectors. Innovations in bio-based production and expanding applications in emerging markets are expected to boost BDO's market value in the coming years.

 

Key Market Drivers:

- Growth in the automotive and textile industries  

- Increasing use of bio-based BDO as a sustainable alternative  

- Expanding applications in pharmaceuticals and electronics  

 

Conclusion

 

1,4-Butanediol (BDO) is an indispensable chemical in the modern industrial landscape. Its versatility, reactivity, and wide-ranging applications make it a vital component across numerous sectors. As industries embrace greener production technologies, BDO's role in driving innovation and sustainability continues to grow.

{CAS 110-63-4 1,4-Butanediol BDO}